Dual Fractions Proteomic Analysis of Silica Nanoparticle Interactions with Protein Extracts

This dual-fraction MS approach provides a more comprehensive understanding of nanoparticle interactions with cellular proteomes. It reveals a novel class of "impacted" proteins, potentially undergoing conformational changes or aggregation due to NP exposure. Further research is needed to elucidate their biological functions and the mechanisms underlying their impact.

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Publication Details

Journal
Materials
Published
2024-10-07
DOI
https://doi.org/10.3390/ma17194909
Citations
2
Primary Topic
Diatoms and Algae Research
Type
article
Field-Weighted Citation Impact
0.35
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Dual Fractions Proteomic Analysis of Silica Nanoparticle Interactions with Protein Extracts

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Dual Fractions Proteomic Analysis of Silica Nanoparticle Interactions with Protein Extracts

Yves Boulard, Marion Schvartz, Céline Henry, Jean-Christophe Aude, Florent Saudrais, Jean‐Philippe Renault, Serge Pin, Stéphane Chédin
article en
2 citations

Abstract

This dual-fraction MS approach provides a more comprehensive understanding of nanoparticle interactions with cellular proteomes. It reveals a novel class of "impacted" proteins, potentially undergoing conformational changes or aggregation due to NP exposure. Further research is needed to elucidate their biological functions and the mechanisms underlying their impact.

MaterialsVol. 17(19)
Centre National de la Recherche Scientifique (FR), AgroParisTech (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Université Paris-Saclay (FR), Microbiologie de l’alimentation au service de la santé (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Institut de Biologie Intégrative de la Cellule (FR), CEA Paris-Saclay (FR)
Openalex Percentile: Top 44%
Diatoms and Algae Research
0.35
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