Network Analysis of Dysregulated Immune Response to COVID-19 mRNA Vaccination in Hemodialysis Patients

Altogether, our results indicate that constitutive inflammation in ESRD compromises the activation of DCs and NK cells, and, ultimately, their mediation of downstream lymphocytes, leading to a delayed but intact immune response to mRNA vaccination.

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Publication Details

Journal
Vaccines
Published
2024-10-07
DOI
https://doi.org/10.3390/vaccines12101146
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
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article

Network Analysis of Dysregulated Immune Response to COVID-19 mRNA Vaccination in Hemodialysis Patients

Huang Kai, Yue Huang, Yi-Shin Chang, Samantha R Warpecha et al.
Vaccines
Diabetes and associated disorders
article

Network Analysis of Dysregulated Immune Response to COVID-19 mRNA Vaccination in Hemodialysis Patients

Huang Kai, Yue Huang, Yi-Shin Chang, Samantha R Warpecha, Cody Schott, Christian Ascoli, Benjamin A. Turturice, Nandini Sarup, David L. Perkins, Ruth A Cherian, Jessica M. Lee, Christen Vagts, Rhea Goel, Patricia W. Finn, Russell Edafetanure-Ibeh, Sunghyun Hwang, Montserrat H. Martinez
article en

Abstract

Altogether, our results indicate that constitutive inflammation in ESRD compromises the activation of DCs and NK cells, and, ultimately, their mediation of downstream lymphocytes, leading to a delayed but intact immune response to mRNA vaccination.

VaccinesVol. 12(10)
University of New Mexico (US), University of Illinois Chicago (US), University of Colorado Denver (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 80%
Diabetes and associated disorders
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Network Analysis of Dysregulated Immune Response to COVID-19 mRNA Vaccination in Hemodialysis Patients — Huang Kai, Yue Huang, et al. · Vaccines (2024) | TGRS Research Map | TGRS