Rapid Amplification of Cerebrospinal Fluid Pressure as a Possible Mechanism for Optic Nerve Sheath Bleeding in Infants With Nonaccidental Head Injury
A sudden increase in CSF pressure in the cranial cavity can cause a rapid expansion of the ONSAS, which may lead to rupture of the bridging blood vessels. Our study predicts a plausible mechanism for subdural hemorrhage that occurs in abusive head trauma in infants.
Authors
- Moussa A. Zouache (ORCID: https://orcid.org/0000-0003-3689-7748)
- Tamsin A. Spelman (ORCID: https://orcid.org/0000-0002-4991-7931)
- Oliver E. Jensen (ORCID: https://orcid.org/0000-0003-0172-6578)
- Peter S. Stewart (ORCID: https://orcid.org/0000-0002-0971-8057)
- Bindi S. Brook (ORCID: https://orcid.org/0000-0001-9883-4131)
- Robert J. Whittaker (ORCID: https://orcid.org/0000-0001-7775-3383)
Institutions
- University of East Anglia (GB)
- University of Nottingham (GB)
- University of Utah (US)
- University of Cambridge (GB)
- Sainsbury Laboratory (GB)
- University of Manchester (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1167/iovs.65.12.9
- Citations
- 2
- Primary Topic
- Child Abuse and Related Trauma
- Type
- article
- Field-Weighted Citation Impact
- 2.22
Funders
- National Centre for the Replacement, Refinement and Reduction of Animals in Research
- Engineering and Physical Sciences Research Council