Steatotic Liver Disease in Pediatric Obesity and Increased Risk for Youth-Onset Type 2 Diabetes
MASLD, defined by transaminases or diagnosis code, in pediatric obesity is associated with increased risk for youth-onset type 2 diabetes. MASLD interacts synergistically with intermediate hyperglycemia to dramatically increase the risk. Optimal response in obesity treatment reduces type 2 diabetes risk, despite MASLD.
Authors
- Emilia Hagman (ORCID: https://orcid.org/0000-0003-1433-2295)
- Pernilla Danielsson (ORCID: https://orcid.org/0000-0002-4674-2638)
- Resthie Rachmanta Putri (ORCID: https://orcid.org/0000-0002-6659-1937)
- Claude Marcus (ORCID: https://orcid.org/0000-0003-0890-2650)
- Thomas Casswall (ORCID: https://orcid.org/0000-0002-4546-826X)
Institutions
- Karolinska Institutet (SE)
Publication Details
- Journal
- Diabetes Care
- Published
- 2024-10-07
- DOI
- https://doi.org/10.2337/dc24-1236
- Citations
- 21
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.12
Funders
- AstraZeneca
- Novo Nordisk
- Novo Nordisk Fonden
- Center for Innovative Medicine