Post–COVID-19 Condition Fatigue Outcomes Among Danish Residents
In this cohort study, SARS-CoV-2 infection was associated with a subtle increase in self-reported fatigue and postexertional malaise symptoms 2 to 18 months after mild infection. In contrast, individuals hospitalized with acute SARS-CoV-2 experienced a more substantial increase in postacute symptoms. Preexisting psychiatric conditions did not significantly modify the risk of postacute fatigue symptoms. The findings largely captured symptoms following first-time infections in a population where most had been vaccinated. Persons who experienced severe acute infection may benefit from clinical follow-up for fatigue.
Authors
- Steen Ethelberg (ORCID: https://orcid.org/0000-0002-9709-356X)
- Anders Koch (ORCID: https://orcid.org/0000-0001-9205-1048)
- Ingrid Bech Svalgaard
- Nete Munk Nielsen (ORCID: https://orcid.org/0000-0002-0908-6950)
- Lampros Spiliopoulos (ORCID: https://orcid.org/0000-0001-9668-3587)
- Anna Irene Vedel Sørensen (ORCID: https://orcid.org/0000-0002-3877-4592)
- Anders Hviid (ORCID: https://orcid.org/0000-0002-7509-9127)
- Peter Bager (ORCID: https://orcid.org/0000-0002-3577-8459)
- Elisabeth O’Regan (ORCID: https://orcid.org/0000-0002-1310-957X)
- Poul Videbech (ORCID: https://orcid.org/0000-0003-0127-4348)
Institutions
- Statens Serum Institut (DK)
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- Glostrup Hospital (DK)
- Rigshospitalet (DK)
- Sygehus Sønderjylland (DK)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.34863
- Citations
- 1
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- Lundbeckfonden
- Novo Nordisk
- Ministeriet Sundhed Forebyggelse
- H. Lundbeck A/S