Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation
De novo host-graft synapses recapitulate the developmental microstructure of the photoreceptor synapse, and their formation contributes to the light responsiveness after SC-RO transplantation.
Authors
- Yoshiko Takahashi (ORCID: https://orcid.org/0000-0002-1596-7527)
- Ryutaro Akiba (ORCID: https://orcid.org/0000-0001-8078-3794)
- Hung‐Ya Tu (ORCID: https://orcid.org/0000-0002-4868-6262)
- Takayuki Baba (ORCID: https://orcid.org/0000-0002-8178-8391)
- Masayo Takahashi (ORCID: https://orcid.org/0000-0003-1836-6484)
- Michiko Mandai
- Kiminori Toyooka (ORCID: https://orcid.org/0000-0002-6414-5191)
- Tomoyo Hashiguchi
- Yoshihiko Tsukamoto
Institutions
- Chiba University (JP)
- RIKEN Center for Sustainable Resource Science (JP)
- RIKEN Center for Biosystems Dynamics Research (JP)
- Protein Research Foundation (JP)
- Hyogo University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1167/iovs.65.12.8
- Citations
- 9
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.10
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science