Stability and computational analysis of Influenza-A epidemic model through double time delay

Delay factors demonstration has a significant role in controlling a strain of infectious disease instead of a pharmaceutical strategy. According to the World Health Organization (WHO), 3–5 million cases are reported annually and approximately 290,000 to 650,000 respiratory deaths annually. So, in the present study, we develop a delayed mathematical model based on delay differential equations (DDEs) for the influenza epidemic using a deterministic approach by introducing double delay parameters. The four distinct sub-populations are considered susceptible, exposed, infected, and recovered. For the rigorous analysis, the fundamental properties of the model like positivity, boundedness, existence, and uniqueness, were studied. The influenza-free equilibrium (IFE) and influenza-existing equilibrium (IEE), are the two nonnegative equilibrium points that the model demonstrates. Both locally and globally, the asymptotic stability of the equilibrium points of the model is established and shown under specific situations of reproduction number. Additionally, investigated the model's parameter sensitivity and determined the relative sensitivity of each parameter. Both standard and nonstandard methods—such as Euler, Runge-Kutta, and nonstandard finite difference with a delayed sense—are presented to make computational analysis support a dynamical analysis and the best visualization of results. The stability of the non-standard finite difference scheme is thoroughly analyzed around the steady states of the model. Additionally, the results show that the nonstandard finite difference approximation is an efficient, cost-effective method, independent of time step size, to solve such highly nonlinear and complex real-world problems.

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Publication Details

Journal
Alexandria Engineering Journal
Published
2024-10-07
DOI
https://doi.org/10.1016/j.aej.2024.09.098
Citations
3
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
1.19
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article

Stability and computational analysis of Influenza-A epidemic model through double time delay

Ateq Alsaadi, Ali Raza, Umar Shafique, Muhammed Bilal Riaz
3 citations
Alexandria Engineering Journal
COVID-19 epidemiological studies
1.19
article

Stability and computational analysis of Influenza-A epidemic model through double time delay

Ateq Alsaadi, Ali Raza, Umar Shafique, Muhammed Bilal Riaz
article en
3 citations

Abstract

Delay factors demonstration has a significant role in controlling a strain of infectious disease instead of a pharmaceutical strategy. According to the World Health Organization (WHO), 3–5 million cases are reported annually and approximately 290,000 to 650,000 respiratory deaths annually. So, in the present study, we develop a delayed mathematical model based on delay differential equations (DDEs) for the influenza epidemic using a deterministic approach by introducing double delay parameters. The four distinct sub-populations are considered susceptible, exposed, infected, and recovered. For the rigorous analysis, the fundamental properties of the model like positivity, boundedness, existence, and uniqueness, were studied. The influenza-free equilibrium (IFE) and influenza-existing equilibrium (IEE), are the two nonnegative equilibrium points that the model demonstrates. Both locally and globally, the asymptotic stability of the equilibrium points of the model is established and shown under specific situations of reproduction number. Additionally, investigated the model's parameter sensitivity and determined the relative sensitivity of each parameter. Both standard and nonstandard methods—such as Euler, Runge-Kutta, and nonstandard finite difference with a delayed sense—are presented to make computational analysis support a dynamical analysis and the best visualization of results. The stability of the non-standard finite difference scheme is thoroughly analyzed around the steady states of the model. Additionally, the results show that the nonstandard finite difference approximation is an efficient, cost-effective method, independent of time step size, to solve such highly nonlinear and complex real-world problems.

Alexandria Engineering JournalVol. 110
VSB - Technical University of Ostrava (CZ), Taif University (SA), National College of Business Administration and Economics (PK), The University of Chenab, Gujrat, Lebanese American University (LB), University of Gujrat (PK)
Good health and well-being
Openalex Percentile: Top 23%
COVID-19 epidemiological studies
1.19
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