Pfizer pulls sickle cell drug

The pharmaceutical giant Pfizer is pulling its small-molecule drug for mild-to- moderate symptoms of sickle cell anemia, which had been granted accelerated approval. The European Medicines Agency (EMA) raised concerns in July after deaths of participants in the follow-up clinical trials of Oxbryta. The EMA scheduled a meeting last month to discuss “emerging data” about the drug, but Pfizer decided to pull the drug in all markets before that meeting took place.

Authors

Publication Details

Journal
C&EN Global Enterprise
Published
2024-10-07
DOI
https://doi.org/10.1021/cen-10231-buscon15
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Pfizer pulls sickle cell drug

Laura Howes
C&EN Global Enterprise
Hemoglobinopathies and Related Disorders
article

Pfizer pulls sickle cell drug

Laura Howes
article en

Abstract

The pharmaceutical giant Pfizer is pulling its small-molecule drug for mild-to- moderate symptoms of sickle cell anemia, which had been granted accelerated approval. The European Medicines Agency (EMA) raised concerns in July after deaths of participants in the follow-up clinical trials of Oxbryta. The EMA scheduled a meeting last month to discuss “emerging data” about the drug, but Pfizer decided to pull the drug in all markets before that meeting took place.

C&EN Global EnterpriseVol. 102(31)
Openalex Percentile: Top 71%
Hemoglobinopathies and Related Disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.