The Impact of Spliceosome Inhibition in <i>SF3B1</i>-Mutated Uveal Melanoma
This study indicates/suggests that mutated SF3B1 UM cells are more sensitive to the splicing inhibitor E7107 than wild-type SF3B1 UM cells.
Authors
- Harmen J.G. van de Werken (ORCID: https://orcid.org/0000-0002-9794-1477)
- Josephine Q.N. Nguyen (ORCID: https://orcid.org/0000-0002-6428-6226)
- Erwin Brosens (ORCID: https://orcid.org/0000-0001-8235-4010)
- Wojtek Drabarek
- Job van Riet (ORCID: https://orcid.org/0000-0001-7767-7923)
- Robert M. Verdijk (ORCID: https://orcid.org/0000-0003-1437-214X)
- Dion Paridaens (ORCID: https://orcid.org/0000-0001-6762-3614)
- Thierry P. P. van den Bosch
- Tom Brands (ORCID: https://orcid.org/0000-0003-0865-8934)
- Annelies de Klein (ORCID: https://orcid.org/0000-0002-1513-4787)
- Aïsha M. C. H. J. Leeflang
- Emine Kılıç (ORCID: https://orcid.org/0000-0002-6867-3792)
Institutions
- Leiden University Medical Center (NL)
- Rotterdam Eye Hospital (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1167/iovs.65.12.11
- Citations
- 4
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- Stichting Steunfonds Uitzicht