Doxycycline Trap: A Case Report on the Unexpected Development of an Oesophageal Ulcer
The phenomenon of drug-induced mucosal damage has not been reported much in the literature, although over 100 drugs are known to cause this condition. Tetracyclines contribute the most to mucosal damage. The common symptoms are difficulty swallowing, pain while swallowing, and possibly retrosternal pain. The diagnosis is based on upper endoscopy. The therapeutic approach involves discontinuing the causative drug, switching to parenteral fluid intake, and administering proton pump inhibitors and antacids. Proper drug intake in an upright position with plenty of fluids is key to preventing mucosal damage.
Authors
- Nataša Zdravković
- Mladen Maksić (ORCID: https://orcid.org/0000-0001-8259-6060)
- Dušan Radojević (ORCID: https://orcid.org/0000-0002-6287-6310)
- Željko Todorović (ORCID: https://orcid.org/0000-0001-9989-5921)
- Irfan Ćorović
- Đorđe Stevanović (ORCID: https://orcid.org/0000-0001-8234-0962)
- Tijana Veljkovic
- Biljana Milojkovic Kicevska
- Marina Jovanović (ORCID: https://orcid.org/0000-0002-2441-7914)
- Djordje Kralj
- V.B. Djukic
Institutions
- Univerzitet u Novom Pazaru (RS)
- University of Kragujevac (RS)
- State University of Novi Pazar (RS)
- Kliničko Bolnički Centar Zvezdara (RS)
- Clinical Centre of Kragujevac (RS)
Publication Details
- Journal
- Cureus
- Published
- 2024-10-07
- DOI
- https://doi.org/10.7759/cureus.71022
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu