Seizures and Epilepsy in Association With Neurocysticercosis

Neurocysticercosis is one of the main risk factors of seizures and epilepsy in many regions of the world, which are <i>Taenia solium</i>-endemic but resource-constrained to control the parasite. The nosology of seizures and the classification of epilepsy in the context of neurocysticercosis are somewhat uncertain. Many seizures associated with the infection are customarily referred to as "acute symptomatic seizures." The term, however, seems unsuitable. Neither is the condition acute nor does it allow the avoidance of long-term antiseizure medications, as is the case with acute symptomatic seizures, for instance, associated with traumatic brain injury. We propose that seizures be classified according to the evolutionary stage of parenchymal cysticercosis in addition to the conventional classification of seizures and epilepsy and identification of the epileptogenic zone. An often-ignored aspect is the identification of comorbidities, many of which are specific to neurocysticercosis.

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Publication Details

Journal
Neurology
Published
2024-10-07
DOI
https://doi.org/10.1212/wnl.0000000000209865
Citations
15
Primary Topic
Parasitic infections in humans and animals
Type
article
Field-Weighted Citation Impact
6.37

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article

Seizures and Epilepsy in Association With Neurocysticercosis

Christina Coyle, Josemir W. A. S. Sander, Óscar H. Del Brutto, Gagandeep Singh et al.
15 citations
Neurology
Parasitic infections in humans and animals
6.37
article

Seizures and Epilepsy in Association With Neurocysticercosis

Christina Coyle, Josemir W. A. S. Sander, Óscar H. Del Brutto, Gagandeep Singh, Héctor H. García
article en
15 citations

Abstract

Neurocysticercosis is one of the main risk factors of seizures and epilepsy in many regions of the world, which are <i>Taenia solium</i>-endemic but resource-constrained to control the parasite. The nosology of seizures and the classification of epilepsy in the context of neurocysticercosis are somewhat uncertain. Many seizures associated with the infection are customarily referred to as "acute symptomatic seizures." The term, however, seems unsuitable. Neither is the condition acute nor does it allow the avoidance of long-term antiseizure medications, as is the case with acute symptomatic seizures, for instance, associated with traumatic brain injury. We propose that seizures be classified according to the evolutionary stage of parenchymal cysticercosis in addition to the conventional classification of seizures and epilepsy and identification of the epileptogenic zone. An often-ignored aspect is the identification of comorbidities, many of which are specific to neurocysticercosis.

NeurologyVol. 103(9)
Universidad Peruana Cayetano Heredia (PE)
National Institute for Health and Care Research, University College London, Angelini Pharma, Epilepsy Society
Good health and well-being
Openalex Percentile: Top 3%
Parasitic infections in humans and animals
6.37
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