Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research

Both the MTX and TNFi uveitis CTPs can practically be implemented in clinical settings and are currently being utilized across Registry sites. However, in patients starting TNFi therapy, all pilot study participants and most patients across the CARRA Registry were treated with a standard dose of adalimumab. This consensus on the treatment approach underscores its broad acceptance but also limits the applicability of the uveitis TNFi CTP for comparative effectiveness research.

Authors

Institutions

Publication Details

Journal
Pediatric Rheumatology
Published
2024-10-07
DOI
https://doi.org/10.1186/s12969-024-01022-x
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research

L. Santiago, Homaira Rahimi, Heather Van Mater, Bianca Lang et al.
Pediatric Rheumatology
Ocular Diseases and Behçet’s Syndrome
article

Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research

L. Santiago, Homaira Rahimi, Heather Van Mater, Bianca Lang, Jonathan S. Hausmann, Eyal Muscal, Juan Carlos Perfetto, M. Shishov, K. Ede, Lindy McAllister, Jordan Rupp, Steven H. Stern, E. Roth-Wojcicki, Oscar Mwizerwa, Ekemini A. Ogbu, A. Theisen, B. Binstadt, H. Rothermel, N. Vasquez, Seokchan Hong, Aurelien Vallée, Carlos José Caetano Bacha, L. Newhall, Nora G. Singer, Li Hong Idris Lim, L. Barillas-Arias, H. Waite, L. Kovalick, Mona Riskalla, B. Lapin, Risa Alperin, R. Oakes, E. DeSantis, Alisha Akinsete, W. Bernal, Tim Hammond, Bruce R. Stevens, Heather M. Walters, Elaine Flanagan, A. Long, Emily von Scheven, C. Lin, Natalie Rosenwasser, Renee Modica, C. Stingl, Autumn Grim, C. Failing, Anita Dhanrajani, Adam M. Huber, Meredith Riebschleger, Özlem Kudaş, M. Henrickson, Karen James, Onengiya Harry, Myriam Guevara, V. Cartwright, Allison Martin Nguyen, Kaili Widrick, D. Rothman, Lisabeth V. Scalzi, Michael Waterfield, Christina J. DeCoste, S. Kim, M. Curry, Alcyone Artioli Machado, Elizabeth B. Brooks, Kristen McDaniels, Donald P. Goldsmith, L. Hiraki, Susan Canny, Jessica Neely, Amy S. Paller, Kathryn S. Torok, J. Nocton, R. Sheets, Stéphane M. Gagné, M. DeGuzman, Y. Levinsky, D. Fair, Alexei A. Grom, Vidya Sivaraman, L. Vannoy, Ryan Mitacek, M. Ibarra, S. Grevich, Ali Yalçindağ, S. Lieberman, Victoria Westheuser, R. Connor, Peter Weiser, Jeffrey Dvergsten, EP Sloan, Ashley M. Cooper, M. Hamda Natur, Jesse Y. Hsu, Amanda R. Schlefman, T. Klausmeier, N. Delnay, S. Mohan, Andrew J. White, J. Spitznagle, Joanne Drew, Steve Graham, M. Becker, E. Allenspach, Mandy Wat- son, G. Schulert, D.P. Horton, J. Weiss, Rhonda Devine, Ezra M. Cohen, Fatima Barbar‐Smiley, A. Murphy, Marisa S. Klein‐Gitelman, Megan Quinlan‐Waters, Emily A. Smitherman, Simona Nativ, M. Basiaga, T. Lee, A. Reed, Tova Ronis, K. Yomogida, Y. Kimura, T. Symington, I. Ferguson, Austin Dalrymple, Taylor N. LaFlam, Tamar B. Rubinstein, K. Abulaban, Vivian E Saper, E. Mellins, Maleewan Kitcharoensakkul, D. Kingsbury, G. Syverson, Suzanne Ramsey, A. Jackson, M. Hiskey, Shima Yasin, M. Hollander, Evin Rothschild, E. Datyner, L. Spiegel, Melissa A. Lerman, Chris Todd, Susanne M. Benseler, Ramiro Gálvez Valdovinos, C. Seper, Ruth Livny, Atabak Najafi, Sangeeta Sule, I. Balboni, David Siegel, D. Co, M. Holland, Elizabeth Stringer, Ruud H J Verstegen, Y. Sterba Rakovchik, K. Nowicki, Rae S. M. Yeung, S. Tse, E. Wu, Jonathan P. Smith, D. Wahezi, Aamir Raja, Brian A. Walker, A. Lasky, Mohamed Manaa, Heinrike Schmeling, Laura Cannon, John T. Huggins, Jennette P. Moreno, D. Castro, D. Bullock, T. Wright, K. Steigerwald, Aliese Sarkissian, D. Toib, Mindy S. Lo, Randall Cron, D. Dissanayake, Margalit Rosenkranz, Cuoghi Edens, Y. Ingrid Goh, Hülya Bükülmez, David L. Rogers, Deborah M. Levy, Jordan T. Jones, Andrew F. Stephens, Sarah F. Taber, Erica Lawson, J. Fennell, NY Pan, Shoghik Akoghlanian, Donald A. Reiff, C. Tsin, Rebecca Randell, A. Chang-Hoftman, O. Halyabar, E. Schmitt, E. Wershba, Alexis Begezda, Marinka Twilt, D. McCurdy, S. Fadrhonc, Marc D. Natter, Andrea Moyer, S. Balevic, Sarah Lovell, R. Sundel, J. Verbsky, Linda Rodgers, Elke Leisinger, P. Weiss, M. Toth, Tracy V. Ting, F. Dedeoglu, Cindy P. Lawler, Alexis Boneparth, Daniel Glaser, A. Rosado, Catherine A. Bingham, Anna Chen, C. Correll, Nadia Luca, S. Shenoi, Rajdeep Pooni, Angela Byun Robinson, Linda Wagner‐Weiner, Elaine F. Reed, D. Matchett, Elizaveta Limenis, M. Sutter, C. Varghese, Heather Tory, Diana Milojevic, Kate F. Hays, Polly J. Ferguson, M. Stoll, Kevin Baszis, Edward J. Oberle, L. Bermudez-Santiago, Tonia Moore, Jennifer A. Sullivan, Hemalatha Srinivasalu, Lorien Nassi, Esra Meidan, G. Amarilyo, Lisa Johnson, E. Kessler, K. Hickey, Marie A. Amoruso, Julia G. Harris, Samir Vora, Neta Dagan, T. Valcarcel, C. Egla Rabinovich, Marlene R. Miller, Calvin L. Williams, Eileen C. Rife, B. Thomas, Kristen Cook, Naomi Thomas, H. Conlon, C. Hoffart, J. Fuller, A. Taneja, M. Fox, Zanab Mian, J. Padam, Michael Buckley, Mark Gilbert, K. Hayward, Edward M. Behrens, J. MacMahon, Timothy Hahn, Katherine M. Schultz, M. Brothers, Andrew T. Knight, K. Kaidar, Margaret H. Chang, Peter A. Nigrović, M. J. Horwitz, John H. McColl, Sheila T. Angeles‐Han, Jennifer Twachtman‐Bassett, Caitlan Swaffar, J. Shirley, S. Armendariz, T. Bigley, T. Tanner, E. Hammelev, Alice Zhu, Kendall B. Corbin, Noelle M. Drapeau, Beth S. Gottlieb, Emily M. Fox, Livie Huie, D. Durkee, Y. Zhang, A. Parsons, L. Moorthy, H. Stapp, Barbara P Blackmon, Miriam Peskin, Aimee O. Hersh, Chelsey Smith, Ajay Tambralli, S. Kramer, Robert C. Fuhlbrigge, C. Kremer, Rebecca E. Sadun, K. Stewart, Thomas G. Mason, Barbra Murante, B. Puplava, Lucy Mansfield, Laura Lentini, N. Nasah, Kenneth N. Schikler, Saad Syed, Ginger Janow, M. Riordan, Shao Li, Adel F. Almutairi, S. Prahalad, Robin Stevenson, S. Jared, Joyce C. Chang, Nicholas Ling, M. Blakley, Patricia M. Hobday, Scott Canna, Peter Lee, Carole A. Spencer, Alastair D Hay, Ronald M. Laxer, Sivakanthan Kasinathan, Andrew Zeft, Leandra Woolnough, Esi M. Morgan, E. Cassidy, Maricarmen Lopez‐Pena, Amir B. Orandi, Natasha M. Ruth, Lothar Thomas, Amanda L. Patrick, Alysha J. Taxter, L. Imundo, Deirdre De Ranieri, B. Feldman, B. Nolan, K. E. Klein, Nicole Johnson, S. Gorry, Andrew B. Adams, H. Brunner, Justin M. Dean, Jayesh M. Pandya, Karen Onel, S. Tarvin, L. Tate, William G Ambler, S. Panupattanapong, Suzanne Richins, M. Tesher, Joyce Hui‐Yuen, Leslie Favier, Barbara Edelheit, James R. Madison, S. Sabbagh, Janalee Taylor, Lynn Buckley, Priya Patel, Sivia Lapidus, Sam Baxter, MF Perron, J. M. Bridges, Edward Duncan, Grace Lai–Hung Wong, Peter Chiraseveenuprapund, A. Carmela Sagcal Gironella, Patricia Vega‐Fernandez, Bernadette Kienzle, S. Paul, Tom Griffin, Karen D. Moore, J. Rafko, J. Velez, Jayesh Patel, Lori Ponder, Manuela Rodriquez, Yongfeng Zhao, M. Dhalla, Mei‐Chen Lo, L. Fogel, Kyle McBrearty, Dina Kafisheh, S. Patrizi, A. AlBijadi, Andrew Lee, Qing Du, Meili Ma, Rajdeep Kaur, Ying Jiang, L. Robinson, Jamie McDonald, Abdulla Shehab, Megan Lloyd, A Szymański, K. Rouster - Stevens, Kabita Nanda, Ashley Lytch, Raphaël Schneider, Katherine Rampone, K. Dunnock, Y. Elzaki, T. Futch-West, D. Gerstbache, C. Aguiar Lapsia, A. Imlay, K. Nearanz, S. Ogbonnaya-Whittesley, L. Asfaw, J. Schahn, D. Sosna, N. Swayne, T. Thakurdeen, Sarah Mh Vandenbergen, H. Bradfield, Geraldina Lionetti, Mark E. Sherman, Remigio M. Olveda, Philip Kahn, C. Black, Päivi Miettunen, Christine Schütt, N.K. Goswami, A. Eberhard, R. Tal, C. Manos, S. Lvovich, M. Norman Oliver, Tzachy Tal, H L Reid, E. Beil, Lynsey Franklin, M.C. Mannion, C. Figueroa, S. Ardoin, B. Marston, W.K. Stewart, S. Ballinger, T. Davis, Jennifer B. Soep, E. Chalom, John F. Bohnsack, Maura Furey, John Collinge, Valerio Gennaro, Liora Harel, M. Elder, A. Waters, A. Pappo Toledano, Linda Ray, L Henderson, C. Inman
article en

Abstract

Both the MTX and TNFi uveitis CTPs can practically be implemented in clinical settings and are currently being utilized across Registry sites. However, in patients starting TNFi therapy, all pilot study participants and most patients across the CARRA Registry were treated with a standard dose of adalimumab. This consensus on the treatment approach underscores its broad acceptance but also limits the applicability of the uveitis TNFi CTP for comparative effectiveness research.

Pediatric RheumatologyVol. 22(1)
Cincinnati Children's Hospital Medical Center (US), Boston Children's Hospital (US), Seattle Children's Hospital (US), Nationwide Children's Hospital (US), Amgen (United States) (US), Children's Hospital of Philadelphia (US), Harvard University (US), Duke University (US), University of Washington (US), University of Utah (US), Connecticut Children's Medical Center (US), Cincinnati Eye Institute (US), The Ohio State University (US), University of Cincinnati (US), University of Missouri–Kansas City (US), University of Pennsylvania (US)
Rheumatology Research Foundation, National Research Foundation, National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Openalex Percentile: Top 71%
Ocular Diseases and Behçet’s Syndrome
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.