Microstructural Characterization of Dry Powder Inhaler Formulations Using Orthogonal Analytical Techniques
MDRS and dissolution studies of the aerosolized dose of DPIs were successfully used as orthogonal techniques. This study highlights the importance of further assessing in vitro tools that are able to provide a bridge between material attributes or process parameters and in vivo performance.
Authors
- Robert Price (ORCID: https://orcid.org/0000-0003-2897-6948)
- Gonçalo Farias (ORCID: https://orcid.org/0000-0001-9717-4565)
- Bryan Newman (ORCID: https://orcid.org/0000-0002-8259-9277)
- Elizabeth Bielski (ORCID: https://orcid.org/0000-0003-0838-6705)
- William J. Ganley (ORCID: https://orcid.org/0000-0001-8885-2475)
- Denise S. Conti (ORCID: https://orcid.org/0000-0002-6714-1735)
- Sharad Mangal (ORCID: https://orcid.org/0000-0002-4687-2563)
- Jagdeep Shur
Institutions
- Center for Drug Evaluation and Research (US)
- Aptar (United States) (US)
- University of Bath (GB)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1007/s11095-024-03776-1
- Citations
- 4
- Primary Topic
- Inhalation and Respiratory Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.68