Impact of ciprofloxacin with autophagy on renal tubular injury
This indicates that ciprofloxacin enhances autophagy, increasing the amount of free Beclin-1 via phosphorylated Bcl-2, and inhibits caspase activity. Therefore, ciprofloxacin might protect against renal tubular injury through the activation of autophagy in the setting of acute kidney injury.
Authors
- Woo Yeong Park (ORCID: https://orcid.org/0000-0003-2662-2898)
- Yaerim Kim (ORCID: https://orcid.org/0000-0003-1596-1528)
- Jin Hyuk Paek (ORCID: https://orcid.org/0000-0001-8875-1260)
- Ki Sung Ahn
- Seungyeup Han (ORCID: https://orcid.org/0000-0002-7561-6534)
- Kyubok Jin (ORCID: https://orcid.org/0000-0002-7836-8863)
- Jong Won Lee (ORCID: https://orcid.org/0000-0001-7875-1603)
- Sun-Ha Lim
Institutions
- Daegu Catholic University (KR)
- S.P.E.C.I.E.S. (US)
- Keimyung University (KR)
Publication Details
- Journal
- Medicine
- Published
- 2024-10-04
- DOI
- https://doi.org/10.1097/md.0000000000039888
- Citations
- 1
- Primary Topic
- Biomedical Research and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea