Prevention of post-transplant lymphoproliferative disorder in pediatric kidney transplant recipients

PKTR who are EBV-naïve prior to transplantation are expected to have a higher prevalence of EBV DNAemia. We found that PKTR who were EBV seronegative prior to transplantation were less likely to achieve EBV clearance in response to immunosuppression dose reduction. We suggest that rituximab therapy in PKTR may be safe and effective in EBV clearance and PTLD prevention.

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Publication Details

Journal
Pediatric Nephrology
Published
2024-10-07
DOI
https://doi.org/10.1007/s00467-024-06522-2
Citations
4
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
1.13

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article

Prevention of post-transplant lymphoproliferative disorder in pediatric kidney transplant recipients

Shirley Pollack, Moran Plonsky, Rami Tibi, Israel Eisenstein et al.
4 citations
Pediatric Nephrology
Viral-associated cancers and disorders
1.13
article

Prevention of post-transplant lymphoproliferative disorder in pediatric kidney transplant recipients

Shirley Pollack, Moran Plonsky, Rami Tibi, Israel Eisenstein, Daniella Magen, Irina Libinson-Zebegret, Renata Yakobov
article en
4 citations

Abstract

PKTR who are EBV-naïve prior to transplantation are expected to have a higher prevalence of EBV DNAemia. We found that PKTR who were EBV seronegative prior to transplantation were less likely to achieve EBV clearance in response to immunosuppression dose reduction. We suggest that rituximab therapy in PKTR may be safe and effective in EBV clearance and PTLD prevention.

Pediatric NephrologyVol. 40(3)
Technion – Israel Institute of Technology (IL), Rambam Health Care Campus (IL)
Technion-Israel Institute of Technology
Good health and well-being
Openalex Percentile: Top 18%
Viral-associated cancers and disorders
1.13
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