The role and mechanism of CRISPLD2 in skin fibrosis of systemic sclerosis
CRISPLD2 was found to have increased reactivity in TGF-β-induced fibroblasts, and we further confirmed that CRISPLD2 can participate in TGF-β-induced fibroblast fibrosis from multiple perspectives and levels in negative feedback regulation, and investigated the mechanism of CRISPLD2 in fibrosis.
Authors
- Bingying Dai
- Hui Luo (ORCID: https://orcid.org/0000-0001-5593-8563)
- Qiming Meng (ORCID: https://orcid.org/0009-0001-4304-3997)
- Honglin Zhu (ORCID: https://orcid.org/0000-0002-9322-5684)
- Liqing Ding (ORCID: https://orcid.org/0000-0001-5740-7344)
- Chunliu Lv
- Ding Bao
Institutions
- Central South University (CN)
- Hunan Cancer Hospital (CN)
- National Clinical Research (US)
- Hunan Provincial People's Hospital (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1093/rheumatology/keae541
- Citations
- 1
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Natural Science Foundation of Hunan Province