The role of L-arginine as a donor of nitric oxide and the prospects for its use: the review
The article discusses recent research on the effective and safe use of the amino acid L-arginine for medicinal purposes in various pathologies. The practical significance of using L-arginine as a source of nitric oxide is considered. The physiological role of nitric oxide, the main vasodilator, was shown, and its deficiency was found to be a key link in endothelial dysfunction. An analysis of modern studies confirming the effectiveness of L-arginine as a donor of nitric oxide was carried out. Ample evidence suggests that oral administration of L-arginine, within physiological limits, can benefit human health by increasing NO synthesis and hence tissue blood flow.
Authors
- O.I. Margieva (ORCID: https://orcid.org/0000-0002-3557-0586)
- M. T. Margieva
Institutions
- Russian Academy of Sciences (RU)
- North Ossetian State Medical Academy (RU)
Publication Details
- Journal
- Siberian Journal of Clinical and Experimental Medicine
- Published
- 2024-10-01
- DOI
- https://doi.org/10.29001/2073-8552-2024-39-3-34-40
- Citations
- 1
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.33