B cell mechanosensing regulates ER remodeling at the immune synapse

Our results highlight how spatial reorganization of the ER is coupled to the context of antigen recognition and could tune B-cell responses. Additionally, we provide novel evidence that the structural maturation of the ER in plasma cells is initiated during early activation of B-cells.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-10-07
DOI
https://doi.org/10.3389/fimmu.2024.1464000
Citations
5
Primary Topic
T-cell and B-cell Immunology
Type
article
Field-Weighted Citation Impact
1.20

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article

B cell mechanosensing regulates ER remodeling at the immune synapse

María-Isabel Yuseff, Isidora Riobó
5 citations
Frontiers in Immunology
T-cell and B-cell Immunology
1.20
article

B cell mechanosensing regulates ER remodeling at the immune synapse

María-Isabel Yuseff, Isidora Riobó
article en
5 citations

Abstract

Our results highlight how spatial reorganization of the ER is coupled to the context of antigen recognition and could tune B-cell responses. Additionally, we provide novel evidence that the structural maturation of the ER in plasma cells is initiated during early activation of B-cells.

Frontiers in ImmunologyVol. 15
Pontificia Universidad Católica de Chile (CL)
National Institutes of Health
Openalex Percentile: Top 21%
T-cell and B-cell Immunology
1.20
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B cell mechanosensing regulates ER remodeling at the immune synapse — María-Isabel Yuseff, Isidora Riobó · Frontiers in Immunology (2024) | TGRS Research Map | TGRS