Determinants and patterns of self-medication: A comprehensive literature review

Background- Self-medication is a major public health concern practiced worldwide. Research indicates that improper self-medication leads to adverse drug reactions, masks underlying diseases, results in incorrect diagnoses, escalates morbidity, contributes to drug interactions, fosters antibiotic resistance, and strains resources within the healthcare system. Many studies on self-treatment have been published for certain countries or diseases, in addition to specific demographics, including teenagers, senior citizens, and medical pupils. The issue of self-treatment and related antibiotic resistance poses a serious threat to global public health, as there has been a reported rise in self-medication practices over the past ten years. To obtain a thorough yet equivalent awareness of related issues and to make more definitive and practical conclusions for future action planning than those derived from reviews on the topic, it may be beneficial to integrate the current global self-medication data. Therefore, we set out to undertake a study to fully understand the prevalence, sample demographics, medications consumed, target ailment, and reasons for self-medication. Methods-Using the terms "self-medication, “Factors associated with it," and "non-prescription," a systematic review of the literature on self-medication practices was conducted using the databases PubMed, Medline, and Web of Science. The search was limited to cross-sectional study articles published between 2018 and 2022. Results- This analysis comprised 23 studies comprising 8,445 individuals in total. Headache, pain, and fever were shown to be among the most prevalent indications for self-treatment, followed by cold and cough. A summary of 20 studies inferred that Analgesics, antipyretics, and NSAIDs were the most self-practiced medications. Conclusion- Self-medication is widely practiced worldwide. It is critical to control and oversee appropriate self-medication practices through the enactment of strict laws and the involvement of legislators and medical experts. Large-scale public health awareness efforts on a variety of platforms, efficient medication distribution regulation, and legal proceedings against medical malpractice should all receive a great deal of attention. More cross-sectional studies employing a standard methodological framework are needed to have a deeper understanding of the incidence and practices of self-medication worldwide.