Case Report: A Case of Cutaneous T-Cell Lymphoproliferative Disorder vs. Cutaneous Leishmaniasis

Cutaneous T-cell lymphoma is a challenging diagnosis given its rarity and heterogeneity in presentation.The ISCL/EORTC algorithm for the diagnosis of early mycosis fungoides (the most common form of CTCL) highlights the histopathologic presence of a superficial lymphoid infiltrate plus epidermotropism without spongiosis or lymphoid atypia, and the immunopathologic features of CD2,3,5 expression in < 50% of T-cells, CD7 expression in <10% of Tcells and epidermal discordance from expression of CD2,3,5 or CD7 on dermal T-cells as key diagnostic criteria.