Management of Medication-Related Osteonecrosis of the Jaws With Hyperbaric Oxygen Therapy: A Case Report

Medication-related osteonecrosis of the jaw (MRONJ) refers to the condition where the maxillary or mandibular bone becomes exposed and necrotic as a result of bisphosphonate therapy. The number of patients on bisphosphonates is increasing and so are the MRONJ cases. Since the initial data were published in the early 2000s, research into MRONJ has expanded significantly to enhance the understanding of this emerging condition. Various treatment options are available, but none have been established as the definitive "gold standard" for managing this disease. Hyperbaric oxygen therapy (HOT) is one of the treatment modalities for MRONJ, which has generated successful outcomes and an improvement in the quality of life along with a reduction in morbidity, as mentioned in the literature. We validate this by reporting a case of MRONJ successfully treated with HOT.

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Journal
Cureus
Published
2024-10-06
DOI
https://doi.org/10.7759/cureus.70940
Primary Topic
Bone health and treatments
Type
article
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article

Management of Medication-Related Osteonecrosis of the Jaws With Hyperbaric Oxygen Therapy: A Case Report

Yajas Kumar, Nitin Bhagat, Yashmi Jaiswal, Kapila Chakarvarty et al.
Cureus
Bone health and treatments
article

Management of Medication-Related Osteonecrosis of the Jaws With Hyperbaric Oxygen Therapy: A Case Report

Yajas Kumar, Nitin Bhagat, Yashmi Jaiswal, Kapila Chakarvarty, Rakshak Anand
article en

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) refers to the condition where the maxillary or mandibular bone becomes exposed and necrotic as a result of bisphosphonate therapy. The number of patients on bisphosphonates is increasing and so are the MRONJ cases. Since the initial data were published in the early 2000s, research into MRONJ has expanded significantly to enhance the understanding of this emerging condition. Various treatment options are available, but none have been established as the definitive "gold standard" for managing this disease. Hyperbaric oxygen therapy (HOT) is one of the treatment modalities for MRONJ, which has generated successful outcomes and an improvement in the quality of life along with a reduction in morbidity, as mentioned in the literature. We validate this by reporting a case of MRONJ successfully treated with HOT.

CureusVol. 16(10)
National Medical Research Center of Dentistry and Maxillofacial Surgery (RU), Manav Rachna International Institute of Research and Studies (IN)
Good health and well-being
Openalex Percentile: Top 69%
Bone health and treatments
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Management of Medication-Related Osteonecrosis of the Jaws With Hyperbaric Oxygen Therapy: A Case Report — Yajas Kumar, Nitin Bhagat, et al. · Cureus (2024) | TGRS Research Map | TGRS