Base‐Mediated Cascade Reaction of CF<sub>3</sub>‐Imidoyl Sulfoxonium Ylides and Diimides for the Synthesis of Functionalized Amidines
Abstract A base‐mediated cascade reaction of CF 3 ‐imidoyl sulfoxonium ylides (TFISYs) and diimides has been developed for the preparation of functionalized amidines. In the transformation, a cascade nucleophilic addition and subsequent [2,3]‐sigmatropic rearrangement of sulfoxonium ylide occur to enable an intramolecular migration of dimethyl sulfoxide (DMSO). The unexpected result of the developed protocol demonstrates the chameleonic reactivity of TFISYs.
Authors
- Zhengkai Chen (ORCID: https://orcid.org/0000-0002-5556-6461)
- Qihua Chen (ORCID: https://orcid.org/0000-0002-2813-7485)
- Sihao Ling
Institutions
- Zhejiang Sci-Tech University (CN)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2024-10-06
- DOI
- https://doi.org/10.1002/adsc.202400996
- Citations
- 4
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.83
Funders
- Natural Science Foundation of Zhejiang Province