A Study on Clinical and Immunological pattern of Systemic Lupus Erythematosus patients in a Tertiary care Hospital – A Retrospective Study

Introduction Systemic Lupus Erythematosus (SLE) is a Chronic Multisystem Autoimmune disorder that exhibits a wide spectrum of clinical and immunological abnormalities ranging from localized cutaneous involvement to life-threatening systemic involvement. The heterogeneity of SLE manifestations is due to an interplay of genetic, environmental, and hormonal influences[1]. Onset occurs commonly in women of reproductive age, in the third and fourth decades of life, with a Male: Female ratio of about 1:10. The clinical course of the disease is unpredictable with periods of remission and flares.