The potential role of interleukin-6 in the association between inflammation and cognitive performance in obstructive sleep apnea
This study documented an association between inflammation, featured by higher IL-6 serum levels, and both nocturnal hypoxemia and cognitive impairment in OSA patients. Therefore, the increase in IL-6 levels may represent the result of vascular damage and neuroinflammation due to intermittent nocturnal hypoxia and further causing neurocognitive dysfunction in OSA.
Authors
- Sergio Bernardini (ORCID: https://orcid.org/0000-0003-1984-6834)
- Francesca Izzi (ORCID: https://orcid.org/0000-0003-2490-8761)
- Marzia Nuccetelli (ORCID: https://orcid.org/0000-0002-8702-1116)
- Mariana Fernandes (ORCID: https://orcid.org/0000-0002-7005-2805)
- Matteo Spanetta
- Nicola Biagio Mercuri (ORCID: https://orcid.org/0000-0001-6700-7491)
- Giuseppina Laganà (ORCID: https://orcid.org/0000-0003-1841-1046)
- Claudio Liguori (ORCID: https://orcid.org/0000-0003-2845-1332)
- Fabio Placidi (ORCID: https://orcid.org/0000-0002-5214-5581)
- Giorgio Vetrugno
- Alessandro Castelli
- Natalia Manfredi
Institutions
- University of Rome Tor Vergata (IT)
- Fondazione Stella Maris (IT)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1016/j.bbih.2024.100875
- Citations
- 4
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 1.31