Comparison of the ED50 of Ciprofol Combined With or Without Fentanyl for Laryngeal Mask Airway Insertion in Children: A Prospective, Randomized, Open-Label, Dose-Response Trial
In healthy, non-obese Chinese children undergoing elective inguinal hernia repair surgery, fentanyl 1 µg/kg and 2 µg/kg before ciprofol injection significantly reduced the ED50 of ciprofol for attenuating LMA response, with minimal occurrence of severe side effects.
Authors
- Hua‐Cheng Liu
- Fang Chen (ORCID: https://orcid.org/0000-0002-9193-6335)
- Sicong Wang (ORCID: https://orcid.org/0000-0001-8709-0237)
- Wangning Shangguan
- Yan Li (ORCID: https://orcid.org/0009-0004-2353-2453)
- Lezhou Pan
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/dddt.s466603
- Citations
- 10
- Primary Topic
- Airway Management and Intubation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 5.77
Funders
- Wenzhou Medical University
- Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University