Assessment of the Dose-Dependent Effect of Human Platelet Lysate on Wharton’s Jelly-Derived Mesenchymal Stem/Stromal Cells Culture for Manufacturing Protocols
Adjusting the hPL concentration in the culture medium modulates the response of WJ MSCs and enhances their therapeutic potential. Higher hPL concentration promotes increased secretory activity and improves the regenerative capacity of WJ-MSCs, suggesting a promising strategy to optimize MSC-based therapies.
Authors
- Anna Sarnowska (ORCID: https://orcid.org/0000-0001-6974-8592)
- Aleksandra Bzinkowska (ORCID: https://orcid.org/0000-0001-8656-5122)
Institutions
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Stem Cells and Cloning Advances and Applications
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/sccaa.s471118
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.44