In vitro and in vivo study of butyrylfentanyl and 4‐fluorobutyrylfentanyl in female and male mice: Role of the CRF<sub>1</sub> receptor in cardiorespiratory impairment
In this study, we have uncovered a novel mechanism by which synthetic opioids induce respiratory depression, shedding new light on the role of CRF<sub>1</sub> receptors in cardiorespiratory impairments by μ agonists.
Authors
- Sabrine Bilel (ORCID: https://orcid.org/0000-0003-1515-980X)
- Giovanni Serpelloni (ORCID: https://orcid.org/0000-0003-2616-5762)
- Giorgia Corli (ORCID: https://orcid.org/0000-0002-2973-2446)
- Anna Fantinati (ORCID: https://orcid.org/0000-0003-0437-5670)
- Girolamo Calò (ORCID: https://orcid.org/0000-0001-5436-959X)
- Matteo Marti (ORCID: https://orcid.org/0000-0001-8751-2882)
- Marta Bassi (ORCID: https://orcid.org/0009-0008-3753-4627)
- Davide Malfacini (ORCID: https://orcid.org/0000-0003-4562-9550)
- Micaela Tirri (ORCID: https://orcid.org/0000-0001-9337-9184)
- Claudio Trapella (ORCID: https://orcid.org/0000-0002-6666-143X)
- Joaquim Azevedo Neto (ORCID: https://orcid.org/0000-0002-6508-7050)
Institutions
- University of Padua (IT)
- University of Ferrara (IT)
- University of Florida (US)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2024-10-04
- DOI
- https://doi.org/10.1111/bph.17333
- Citations
- 3
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- Università degli Studi di Padova
- Università degli Studi di Ferrara