Heterozygous <scp><i>KCNJ10</i></scp> Variants Affecting Kir4.1 Channel Cause Paroxysmal Kinesigenic Dyskinesia

We identified heterozygous variants of KCNJ10 in PKD. Impaired function of Kir4.1 might lead to abnormal neuronal excitability, which attributed to PKD. © 2024 International Parkinson and Movement Disorder Society.

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Publication Details

Journal
Movement Disorders
Published
2024-10-05
DOI
https://doi.org/10.1002/mds.30025
Citations
7
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
1.64

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article

Heterozygous KCNJ10 Variants Affecting Kir4.1 Channel Cause Paroxysmal Kinesigenic Dyskinesia

Xiaoping Tong, Li Hua Cao, Jingying Wu, Xinghua Luan et al.
7 citations
Movement Disorders
Ion channel regulation and function
1.64
article

Heterozygous KCNJ10 Variants Affecting Kir4.1 Channel Cause Paroxysmal Kinesigenic Dyskinesia

Xiaoping Tong, Li Hua Cao, Jingying Wu, Xinghua Luan, Ping Zhong, Qing Liu, Lan Zheng, Xiaoqi Hong, Kan Fang, Wotu Tian, Zaiwei Zhou, Xin Fu, Beisha Tang, Li Wu, Ziyi Li, Xiao‐Rong Liu, Mei Zhang, Yuwu Zhao, Xiaojun Huang, Xunhua Li, Xin Cheng, Shendi Chen, Xiaoli Liu
article en
7 citations

Abstract

We identified heterozygous variants of KCNJ10 in PKD. Impaired function of Kir4.1 might lead to abnormal neuronal excitability, which attributed to PKD. © 2024 International Parkinson and Movement Disorder Society.

Movement DisordersVol. 39(12)
Central South University (CN), Sun Yat-sen University (CN), Shanghai Jiao Tong University (CN), Anhui University of Science and Technology (CN), Anhui Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Fudan University (CN), Peking Union Medical College Hospital (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Shanghai Children's Medical Center (CN), Shanghai CASB Biotechnology (China) (CN), Shanghai Ninth People's Hospital (CN), Minhang District Central Hospital (CN), Songjiang District Central Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Shanghai First People's Hospital (CN), Shanghai Sixth People's Hospital (CN), Xiangya Hospital Central South University (CN), Guangzhou Medical University (CN)
Shanghai Municipal Health Commission, National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, Shanghai Hospital Development Center, Program of Shanghai Academic Research Leader, Scientific and Innovative Action Plan of Shanghai, Postdoctoral Science Foundation of Shanghai Municipality
Openalex Percentile: Top 16%
Ion channel regulation and function
1.64
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