High Frequency of Artemisinin Partial Resistance Mutations in the Great Lakes Region Revealed Through Rapid Pooled Deep Sequencing
K13 mutations are rapidly expanding in the region, further endangering control efforts with the potential of engendering partner drug resistance.
Authors
- David Giesbrecht (ORCID: https://orcid.org/0000-0003-2498-4705)
- Neeva Wernsman Young (ORCID: https://orcid.org/0000-0002-0131-7670)
- Moses Ntaro (ORCID: https://orcid.org/0000-0001-7944-4082)
- Jean-Baptiste Mazarati (ORCID: https://orcid.org/0000-0003-4549-9725)
- Pierre Gashema (ORCID: https://orcid.org/0000-0001-9348-0936)
- Jeffrey A. Bailey (ORCID: https://orcid.org/0000-0002-6899-8204)
- Tharcisse Munyaneza
- Oliver John Watson (ORCID: https://orcid.org/0000-0003-2374-0741)
- Rebecca Kirby
- Rebecca Crudale (ORCID: https://orcid.org/0000-0002-0789-4196)
- Edgar Mugema Mulogo (ORCID: https://orcid.org/0000-0003-3859-453X)
- Deus S. Ishengoma (ORCID: https://orcid.org/0000-0003-2040-3416)
- Felicien Maisha
- Ross M. Boyce (ORCID: https://orcid.org/0000-0002-9489-6324)
- Lucy Okell (ORCID: https://orcid.org/0000-0001-7202-6873)
- Corine Karema (ORCID: https://orcid.org/0000-0002-6099-7768)
- Rule Budodo (ORCID: https://orcid.org/0000-0003-0297-9219)
- Jonathan J. Juliano (ORCID: https://orcid.org/0000-0002-0591-0850)
- Celine I. Mandara (ORCID: https://orcid.org/0000-0003-4317-4425)
- Stan Hangi
- Grace K. Kanyankole
- Fred Mwebembezi
- Alec Leonetti
- Vincent Iradukunda
- Ntwari Jean Bosco
Institutions
- University of North Carolina at Chapel Hill (US)
- Mbarara University of Science and Technology (UG)
- Brown University (US)
- Kampala International University in Tanzania (TZ)
- INES-Ruhengeri (RW)
- University of Global Health Equity (RW)
- Rwanda Biomedical Center (RW)
- National Institute for Medical Research (TZ)
- Imperial College London (GB)
- Africa University (ZW)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1093/infdis/jiae475
- Citations
- 25
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 13.57
Funders
- Mbarara University of Science and Technology
- Medical Research Council
- National Institute of Allergy and Infectious Diseases