<scp>Matrix‐assisted laser desorption/ionization</scp> mass spectrometry imaging as a new tool for molecular histopathology in epilepsy surgery
This is the first study that explores the potential application of MALDI-MSI in epilepsy postsurgery fixed tissue, by utilizing the well-characterized FCDIIb features as a model. Extending these preliminary analyses to a larger cohort of patients will generate spectral libraries of molecular signatures that discriminate tissue features and will contribute to patient phenotyping.
Authors
- Michele Rizzi (ORCID: https://orcid.org/0000-0002-7936-6536)
- Rita Garbelli (ORCID: https://orcid.org/0000-0002-6475-4974)
- Marco de Curtis (ORCID: https://orcid.org/0000-0001-7443-6737)
- Italia Bongarzone (ORCID: https://orcid.org/0000-0003-2530-9170)
- Giulia Capitoli (ORCID: https://orcid.org/0000-0002-8178-2440)
- Francesco Deleo (ORCID: https://orcid.org/0000-0003-0808-3042)
- Claudio Caccia (ORCID: https://orcid.org/0000-0002-8796-0949)
- Laura Tassi (ORCID: https://orcid.org/0000-0002-0632-7296)
- Dalia De Santis (ORCID: https://orcid.org/0000-0002-2519-2067)
- Cinzia Cagnoli (ORCID: https://orcid.org/0000-0001-6863-6687)
- L Rossini (ORCID: https://orcid.org/0000-0003-3571-8779)
Institutions
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Epilepsia
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1111/epi.18136
- Citations
- 4
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- Ministero della Salute