Effect of 0.5% and 1% glucose intake on tear production in euglycemic

Background: Tear production increases ocular surface health and improves visual clarity. Which facilitates the physical activity comfortably. Different dosages of glucose intake had a significantly varying impact on tear production in euglycemic, initially decreasing followed by an increase. Objective: to compare the effect of 0.5% and 1% glucose intake on tear production in euglycemic. Methodology: A quasi-experimental study was conducted with n=200 participants at Irfan Eye Care Hospital Peshawar, from September 2022 to May 2023. The participants were euglycemic without any ocular and systemic pathology and determined its effect on tear production. The participants were divided into two groups equally for 0.5% and 1% glucose intake. Tear production was measured at baseline, after 60 minutes, 90 minutes, 120 minutes, and 150 minutes with the Schirmer test. Results: There was a significant reduction of tear production from baseline to 120 minutes (p<0.05) than rise in both groups. While when compared, no significant (p≥0.05) difference at each assessment level. Conclusion: there was similar effect of 0.5% and 1% glucose concentration intake on tear production Keywords: fasting blood sugar; glucose; hyperglycaemia; tear production; dry eye disease