Shenmai injection improves lipid metabolism in post-myocardial infarction heart failure based on network pharmacology and experimental validation
Collectively, our findings suggest that SMI enhances myocardial lipid metabolism and ameliorates pMIHF by upregulating the PPARα/SIRT1/PGC1α pathway.
Authors
- Lifang Ye (ORCID: https://orcid.org/0000-0002-6748-4690)
- Gui Fen Yang (ORCID: https://orcid.org/0000-0002-8093-4422)
- Jing Yang (ORCID: https://orcid.org/0000-0001-9097-5810)
- Ting Zeng (ORCID: https://orcid.org/0009-0007-3938-5816)
- Man Zhao (ORCID: https://orcid.org/0009-0006-3817-2731)
- Lihong Wang
Institutions
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38648
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.47