The clinical application of metagenomic next-generation sequencing in immunocompromised patients with severe respiratory infections in the ICU

mNGS shows significant value in detecting pathogens in immunocompromised patients with SRIs in ICU. For immunocompromised patients who respond poorly to empirical treatment, mNGS can provide an etiological basis, helping adjust antibiotic regimens more precisely and thereby improving patient prognosis.

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Publication Details

Journal
Respiratory Research
Published
2024-10-05
DOI
https://doi.org/10.1186/s12931-024-02991-z
Citations
20
Primary Topic
Nosocomial Infections in ICU
Type
article
Field-Weighted Citation Impact
8.44
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The clinical application of metagenomic next-generation sequencing in immunocompromised patients with severe respiratory infections in the ICU

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article

The clinical application of metagenomic next-generation sequencing in immunocompromised patients with severe respiratory infections in the ICU

Jiancheng Zhuge, Junjie Zhao, Honglong Fang, Yong Sun, Kai Guo, Jing Tang, Kaiyu Wang
article en
20 citations

Abstract

mNGS shows significant value in detecting pathogens in immunocompromised patients with SRIs in ICU. For immunocompromised patients who respond poorly to empirical treatment, mNGS can provide an etiological basis, helping adjust antibiotic regimens more precisely and thereby improving patient prognosis.

Respiratory ResearchVol. 25(1)
Zhejiang Chinese Medical University (CN), Wenzhou Medical University (CN), Quzhou City People's Hospital (CN), Quzhou College of Technology (CN), Quzhou University (CN)
Good health and well-being
Openalex Percentile: Top 2%
Nosocomial Infections in ICU
8.44
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