Inhibition of hepatitis B virus through PPAR-JAK/STAT pathway modulation by electroacupuncture and tenofovir disoproxil fumarate combination therapy
E_T more effectively inhibited HBV replication, showing superior antigen inhibition, particularly HBsAg, than TF alone. This may be due to PPAR-JAK/STAT pathway regulation, suggesting E_T as a potential adjuvant therapy for CHB, especially in achieving a functional cure.
Authors
- Zhaofang Bai (ORCID: https://orcid.org/0000-0003-1049-6882)
- Xiaohe Xiao (ORCID: https://orcid.org/0000-0002-2836-2738)
- Feilin Ge
- Xiao Guo (ORCID: https://orcid.org/0000-0002-1495-103X)
- Yang Chen (ORCID: https://orcid.org/0000-0003-4749-3060)
- Shanshan Zhang (ORCID: https://orcid.org/0000-0002-9638-1850)
- Luo Chen (ORCID: https://orcid.org/0000-0003-0727-9545)
- Yan Yang (ORCID: https://orcid.org/0000-0001-7075-3428)
- Chenglin Tang (ORCID: https://orcid.org/0000-0002-9628-9616)
- Yunhao Yang (ORCID: https://orcid.org/0000-0002-7199-2508)
- Junyuan Deng
Institutions
- Chinese PLA General Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1016/j.intimp.2024.113304
- Citations
- 5
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- National Natural Science Foundation of China