7201 Association of Chronotype and Glycemic Control Among Patients with Diabetes Mellitus: A Single Center Study

Abstract Disclosure: N.D. Nunez: None. O.C. Dampil: None. A.C. Ong Lopez: None. Chronotype preference is an emerging risk factor to the development of diabetes mellitus and poor glycemic outcomes. This study aims to determine the association of chronotype based on the Munich Chronotype questionnaire among patients with diabetes mellitus and their level of glycemic control. This is a cross sectional analytical research study conducted at the outpatient department at St. Luke’s Medical Center Quezon City from June 1 to October 31, 2023. Inclusion criteria were adults above 18 years of age who were diagnosed with diabetes, and on oral hypoglycemic medication and/or insulin therapy for at least 6 months. Excluded were those with diagnosed sleep wake disorders, obstructive sleep apnea, pregnant or lactating women, night-shift workers, and those on medications that affect sleep patterns. Among the 290 participants evaluated, majority had early chronotypes (n=250) compared to late chronotypes (n=40). There was no statistical difference between the two groups in terms of the demographic, clinical and laboratory data. Chi-square was done to compare the groups in terms of HBA1c level, and the result was not significant (p=0.3124), indicating that the early and late chronotype groups have the same likelihood of having controlled or uncontrolled HBA1c. The Breslow-day test for homogeneity of odds ratio was done to compare the groups in terms of HBA1c level and use of two or more oral medications and insulin, and the result was not significant (p=0.9281), indicating that the relationship between Hba1c level and use of two or more oral medications and insulin is relatively the same for both chronotypes. In conclusion, there appears to be no influence of chronotype on glycemic control among diabetes mellitus treated Filipino patients. Presentation: 6/3/2024