9369 Hyperglycemia On Admission And The Risk Of Complications In Patients With Hip Fractures

Abstract Disclosure: A. Hassan: None. S. Almardini: None. F. Arafa: None. L. Aoun: None. Hyperglycemia is associated with medical complications such as poor wound healing, immunocompromised state, prolonged hospital stay, and even death. Studies have shown that patients with type II diabetes who sustain a hip fracture have an increased risk of mortality, presumably due to the increased risk of post-operative complications like postoperative pneumonia, deep surgical site infections, and postoperative delirium. Our study aims to determine if initial glucose on admission can be used as a prognostic factor for 30-day mortality and 30-day readmission in patients presenting with hip/femur fractures who also underwent surgical repair. All patients admitted to the Northwell hospital system between 6/2022 and 7/2023 for hip/femur fractures and underwent a surgical repair above the age of 50 were analyzed for this retrospective chart review study. Patients were divided into three groups based on the initial glucose value derived from BMP/CMP (ranges: glucose <140, glucose 140-200, and glucose >200). Higher glucose ranges were used as patients fasting status could not be determined. In each glucose range group, we analyzed 30-day mortality and 30-day readmission rate. Logistic regression was utilized to assess the odds of 30-day mortality and 30-day readmission as a function of initial glucose levels on admission, adjusting for BMI category, malnutrition status, and CKD stage. Adjusted odds ratios and 95% confidence intervals were computed. The original dataset contained 3158 observations. After excluding patients that did not receive a surgical intervention during their stay (n = 752), the sample size decreased to 2406. There were 50 patients that had been admitted twice during the study period, the second visit excluded from analysis, bringing the final sample size to 2356 subjects.Initial glucose on admission was not significantly associated with 30-day mortality (p = 0.8), or with 30-day readmission (p = 0.9) after adjusting for malnutrition status, BMI, and CKD. Based on the Hosmer and Lemeshow Goodness-of-Fit Test, the data fit the model well for the 30-day mortality but poorly for the 30-day readmission. Despite the well-established associations between hyperglycemia and adverse health outcomes, our study did not identify a significant association between initial glucose on admission and 30-day mortality or 30-day readmission, even after adjusting for factors such as malnutrition status, BMI, and CKD. The lack of statistical significance in the adjusted analyses suggests that other factors may play a more substantial role in predicting these outcomes in the specified patient population. Presentation: 6/2/2024