CD73 alleviates osteoarthritis by maintaining anabolism and suppressing catabolism of chondrocytes extracellular matrix
This work showed that CD73 might be one of the biological therapeutic targets of OA, which would provide a reference for future novel treatment strategy of OA.
Authors
- Ruiyang Jiang (ORCID: https://orcid.org/0000-0002-4926-2111)
- Maochun Wang (ORCID: https://orcid.org/0000-0002-6056-1606)
- Fufei Chen
- Rui Wu (ORCID: https://orcid.org/0000-0003-0110-4912)
- Guihua Tan (ORCID: https://orcid.org/0000-0003-4727-5522)
- Weitong Li (ORCID: https://orcid.org/0000-0003-3267-3085)
- Yuan Liu (ORCID: https://orcid.org/0000-0002-6408-8887)
- Ya Xie
- Hu Guo (ORCID: https://orcid.org/0000-0001-7074-5508)
- Zizheng Liu (ORCID: https://orcid.org/0000-0002-3831-7068)
- Jiawei Li (ORCID: https://orcid.org/0000-0002-4514-7589)
- Dongquan Shi (ORCID: https://orcid.org/0000-0001-7153-9327)
- Zhongyang Lv (ORCID: https://orcid.org/0009-0003-1796-6979)
- Ziying Sun
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Wenzhou Medical University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Nanjing Drum Tower Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1016/j.jot.2024.08.014
- Citations
- 4
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Science Foundation
- National Children's Research Centre
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Six Talent Peaks Project in Jiangsu Province