Are Systemic Inflammation Markers Reliable for Diagnosing Intrahepatic Cholestasis of Pregnancy? A Retrospective Cohort Study
Systemic inflammation indices such as SII and NLR offer a cost-effective and rapid means of diagnosing ICP, potentially complementing or surpassing traditional biomarkers like bile acid levels and liver function tests (LFTs). These indices can be easily integrated into routine clinical practice, providing timely intervention to improve maternal and fetal outcomes. Further research is warranted to confirm these findings and establish standardized protocols for their use in ICP management.
Authors
- Sadun Sucu (ORCID: https://orcid.org/0000-0003-3758-0136)
- Alperen Aksan (ORCID: https://orcid.org/0000-0001-7623-3589)
- Ali Turhan Çağlar (ORCID: https://orcid.org/0000-0002-7022-3029)
- Fahri Burçin Fıratlıgil (ORCID: https://orcid.org/0000-0002-4499-3492)
- Sadullah Özkan (ORCID: https://orcid.org/0000-0003-2432-1434)
- Yıldız Akdaş Reis (ORCID: https://orcid.org/0000-0001-9345-6899)
- Ahmet Kurt (ORCID: https://orcid.org/0000-0002-7454-7557)
- Serap Topkara Sucu (ORCID: https://orcid.org/0000-0002-9187-2941)
- Dilara Kurt (ORCID: https://orcid.org/0000-0002-1492-0305)
- Burcu G. Öztürk
Institutions
- Zübeyde Hanim Maternity Hospital (TR)
- Memorial Ankara Hospital (TR)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1111/aji.13937
- Citations
- 6
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 3.26