BL-918 alleviates oxidative stress in rats after subarachnoid hemorrhage by promoting mitophagy through the ULK1/PINK1/Parkin pathway
BL-918 improved both short-term and long-term neurological impairments in rats after SAH and reduced oxidative stress by promoting mitophagy, at least partially through the ULK1/PINK1/Parkin signaling pathway.
Authors
- Qiaowei Wu (ORCID: https://orcid.org/0000-0001-9454-1411)
- Yuxiao Meng
- Kaikun Yuan
- Jiaxing Dai (ORCID: https://orcid.org/0000-0001-5916-9124)
- Bowen Sun (ORCID: https://orcid.org/0000-0003-1536-239X)
- Yuchen Li (ORCID: https://orcid.org/0009-0009-9141-9627)
- Shancai Xu (ORCID: https://orcid.org/0000-0002-1111-2409)
- Yongzhi Zhang (ORCID: https://orcid.org/0000-0003-4047-5345)
- Huaizhang Shi (ORCID: https://orcid.org/0009-0007-3338-0037)
- Jinshuo Yang (ORCID: https://orcid.org/0009-0000-0460-0263)
- Shuai Lan (ORCID: https://orcid.org/0009-0006-8975-8345)
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Free Radical Biology and Medicine
- Published
- 2024-10-04
- DOI
- https://doi.org/10.1016/j.freeradbiomed.2024.10.261
- Citations
- 7
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- Harbin Medical University
- National Natural Science Foundation of China
- Wu Jieping Medical Foundation