Circular RNA TAF4B targeting MFN2 accelerates cell growth in bladder cancer through p27 depression and AKT activation
In conclusion, the physical binding of circTAF4B to MFN2 is a crucial process in the tumorigenesis and progression of BCa. Targeting circTAF4B or its complexes may have potential as a therapeutic strategy for BCa diagnosis and treatment.
Authors
- Jiajia Xu (ORCID: https://orcid.org/0000-0002-6084-2029)
- Xiaohui Zhu (ORCID: https://orcid.org/0000-0001-9146-8909)
- Xiaofeng Li (ORCID: https://orcid.org/0000-0002-3888-6359)
- Yiting Wang (ORCID: https://orcid.org/0000-0001-8599-2165)
- Xiaoting Zhang (ORCID: https://orcid.org/0000-0002-1328-4255)
- Guangzhen Zhuang
Institutions
- Peking University Shenzhen Hospital (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shenzhen Technology University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-04
- DOI
- https://doi.org/10.3389/fimmu.2024.1477196
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province