Unraveling the ecological landscape of mast cells in esophageal cancer through single-cell RNA sequencing
These findings illuminate the complex interactions within the tumor microenvironment of EC and suggest that targeting specific MCs subtypes, particularly via the <i>EGFR</i> signaling pathway, may present novel therapeutic strategies. This study establishes a comprehensive immune map of EC, offering insights for improved treatment approaches.
Authors
- Zhikai Xiahou
- Shengyi Zhang (ORCID: https://orcid.org/0000-0002-4542-4523)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0002-0581-9707)
- Shunqing Zuo
- Jialong Xue
- Yi Zhang (ORCID: https://orcid.org/0000-0001-6223-4724)
Institutions
- Southwest Medical University (CN)
- Beijing Sport University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-04
- DOI
- https://doi.org/10.3389/fimmu.2024.1470449
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28