Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon – Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial

This first randomized controlled trial investigating PZQ in pregnant women with S. haematobium found PZQ to be safe, effective, and reducing maternal anemia. We recommend treating confirmed infections to prevent morbidity in pregnant women.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2024-10-04
DOI
https://doi.org/10.1016/j.ijid.2024.107253
Citations
4
Primary Topic
Parasites and Host Interactions
Type
article
Field-Weighted Citation Impact
2.06

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article

Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon – Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial

Bayodé Roméo Adégbitè, Paul L. A. M. Corstjens, Jean-Claude Dejon-Agobé, Jacob Gerstenberg et al.
4 citations
International Journal of Infectious Diseases
Parasites and Host Interactions
2.06
article

Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon – Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial

Bayodé Roméo Adégbitè, Paul L. A. M. Corstjens, Jean-Claude Dejon-Agobé, Jacob Gerstenberg, Andrea Kreidenweiss, Govert J. van Dam, Pytsje T. Hoekstra, Moustapha Nzamba Maloum, Mario Recker, Jean‐Ronald Edoa, Jeannot Fréjus Zinsou, Paul Alvyn Nguema Moure, Brice Meulah, Romuald Beh, Yabo Josiane Honkpéhèdji, Bertrand Lell, Saïdou Mahmoudou, Michael Ramharter, Romeo Laclong Lontchi, Peter G Kremsner, Ayôla Akim Adégnika, Selidji T Agnandji
article en
4 citations

Abstract

This first randomized controlled trial investigating PZQ in pregnant women with S. haematobium found PZQ to be safe, effective, and reducing maternal anemia. We recommend treating confirmed infections to prevent morbidity in pregnant women.

International Journal of Infectious DiseasesVol. 149
Universität Hamburg (DE), University of Exeter (GB), Leiden University Medical Center (NL), Centre de Recherche Médicales de Lambaréné (GA), University Medical Center Hamburg-Eppendorf (DE), German Center for Infection Research (DE), Bernhard Nocht Institute for Tropical Medicine (DE)
European and Developing Countries Clinical Trials Partnership
Openalex Percentile: Top 14%
Parasites and Host Interactions
2.06
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