Nanoscale antibacterial coatings incorporating silver nanoparticles derived by plasma techniques – A state-of-the-art perspective

The challenges presented by medical device associated infections have triggered enormous efforts to design, produce and integrate antibacterial surface coating technologies. Amongst other methods, plasma-based coatings have generated considerable interest due to their unique technological and sustainability advantages. In this perspective, we provide a concise overview of the different plasma-based approaches that were developed over the last two decades for generations of nanoscale antibacterial coatings incorporating silver nanoparticles. We begin with discussing the need for antibacterial coatings and the specific benefits of plasma technology and antibacterial silver. We then classify the reported approaches in terms of direct and multistep methods and critically assess the pros and cons of each approach. We conclude this assessment with a discussion and the authors perspective for the future of the field. • Plasma polymerisation is an environmentally friendly procedure to coat surfaces. • AgNPs are potent antimicrobial agents with high potential for translation. • AgNPs are an attractive non-antibiotic solution to antimicrobial resistance. • AgNPs have been incorporated into plasma-polymer coatings through varied methods. • Rational fabrication can promote antibacterial activity and minimize toxicity.