Mangiferin Ameliorates CCl4-Triggered Acute Liver Injury by Inhibiting Inflammatory Response and Oxidative Stress: Involving the Nrf2-ARE Pathway

CCl<sub>4</sub> can induce liver injury, while treatment with MGF mitigates ALI by inhibiting oxidative stress, inflammation, and apoptosis. The protective mechanism of MGF is mediated by the Nrf2-ARE pathway activation.

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Publication Details

Journal
Journal of Inflammation Research
Published
2024-10-01
DOI
https://doi.org/10.2147/jir.s476288
Citations
9
Primary Topic
Mangiferin and Mango Extracts
Type
article
Field-Weighted Citation Impact
6.45
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article

Mangiferin Ameliorates CCl4-Triggered Acute Liver Injury by Inhibiting Inflammatory Response and Oxidative Stress: Involving the Nrf2-ARE Pathway

Yutong Zhang, Rui Dong, Caixing Shi, Z. Y. You et al.
9 citations
Journal of Inflammation Research
Mangiferin and Mango Extracts
6.45
article

Mangiferin Ameliorates CCl4-Triggered Acute Liver Injury by Inhibiting Inflammatory Response and Oxidative Stress: Involving the Nrf2-ARE Pathway

Yutong Zhang, Rui Dong, Caixing Shi, Z. Y. You, Menghan Yang, Yiran Tian, Xiaojin Li, Xiaoyu Zhu, Yueyao Li, H. Quan, Hao Xu, Yanan Shang
article en
9 citations

Abstract

CCl<sub>4</sub> can induce liver injury, while treatment with MGF mitigates ALI by inhibiting oxidative stress, inflammation, and apoptosis. The protective mechanism of MGF is mediated by the Nrf2-ARE pathway activation.

Journal of Inflammation ResearchVol. Volume 17
Jining Medical University (CN)
Zero hunger
Openalex Percentile: Top 4%
Mangiferin and Mango Extracts
6.45
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