Discovery of plasma biomarkers related to blood-brain barrier dysregulation in Alzheimer’s disease
In conclusion, a 5-protein panel is shown to effectively identify AD patients, with evidence of disease specificity and biological validity. Future research should investigate the mechanism of protein leakage through the blood-brain barrier.
Authors
- Keng‐Hwee Chiam (ORCID: https://orcid.org/0000-0002-8987-8463)
- Yuet Ruh Dan
Institutions
- Agency for Science, Technology and Research (SG)
- Nanyang Technological University (SG)
- Bioinformatics Institute (SG)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2024-10-04
- DOI
- https://doi.org/10.3389/fbinf.2024.1463001
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.65