RNA Sequencing Analysis of Monocytes Exposed to Airway Fluid From Children With Pediatric Acute Respiratory Distress Syndrome
We identified gene networks important to the PARDS airway immune response using bulk RNA sequencing from a monocyte reporter assay that exposed monocytes to airway fluid from intubated children with and at-risk for PARDS. Mechanistic investigations are needed to validate our findings.
Authors
- Rishikesan Kamaleswaran (ORCID: https://orcid.org/0000-0001-8366-4811)
- Michael J. Ripple
- Anne M. Fitzpatrick (ORCID: https://orcid.org/0000-0002-2933-5926)
- Mallory Tidwell
- Jocelyn R. Grunwell (ORCID: https://orcid.org/0000-0003-4289-6469)
- Susan T. Stephenson (ORCID: https://orcid.org/0000-0003-4202-1929)
- Min Huang (ORCID: https://orcid.org/0000-0002-2844-5680)
Institutions
- Georgia Institute of Technology (US)
- Emory University (US)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1097/cce.0000000000001125
- Citations
- 1
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42