Tolvaptan and the role of kidney aquaporin-2 abundance in managing volume overload in patients with CKD
Tolvaptan showed efficacy and safety in managing volume overload in CKD patients. The expression of AQP2 in the collecting duct could predict tolvaptan's efficacy.This study protocol was approved by the Ethics Committee of Zhongda Hospital Affiliated to Southeast University (Approval No. 2023ZDSYLL180-P01, Clinical Trial Registration No. ChiCTR2300075274, Trial Registration Link: https://www.chictr.org.cn/guide.html).
Authors
- Bi‐Cheng Liu (ORCID: https://orcid.org/0000-0002-4584-1853)
- Bin Wang (ORCID: https://orcid.org/0000-0003-1606-5004)
- Xiaomin Li (ORCID: https://orcid.org/0000-0002-0051-3354)
- Fengmei Wang (ORCID: https://orcid.org/0000-0002-4287-2603)
- Yan Yang (ORCID: https://orcid.org/0000-0002-1756-1803)
- Xiaoliang Zhang (ORCID: https://orcid.org/0000-0002-0433-4636)
- Ri‐Ning Tang (ORCID: https://orcid.org/0000-0003-3190-7687)
- Yu Yan
- Hong Liu (ORCID: https://orcid.org/0000-0002-2380-8286)
Institutions
- Zhongda Hospital Southeast University (CN)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1093/ckj/sfae303
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Changjiang Scholar Program of Chinese Ministry of Education