Plasma procalcitonin and urine interleukin-8, neutrophil gelatinase–associated lipocalin, and calprotectin in the diagnostic process of a urinary tract infection at the emergency department
Plasma procalcitonin could not accurately diagnose UTI. Urine IL-8, NGAL, and calprotectin showed no additional value relative to routine diagnostics, except a minor improvement in patients with leukopenia. These urine biomarkers seem to predominantly reflect leukocyturia.
Authors
- Greetje A. Kampinga (ORCID: https://orcid.org/0000-0003-0324-6383)
- Coen A. Stegeman (ORCID: https://orcid.org/0000-0002-0224-0927)
- Jan C. ter Maaten (ORCID: https://orcid.org/0000-0002-0353-4011)
- Stephanie J. M. Middelkoop (ORCID: https://orcid.org/0000-0001-8138-3485)
- Anneke C. Muller Kobold (ORCID: https://orcid.org/0000-0003-3457-4179)
- L. Joost van Pelt (ORCID: https://orcid.org/0000-0001-5538-1806)
- Robert Keekstra
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2024-10-05
- DOI
- https://doi.org/10.1016/j.ijid.2024.107257
- Citations
- 2
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Universitair Medisch Centrum Groningen