Diagnostic Performance of Ultrasound vs Ultrasound-Guided FNAC in Thyroid Nodules: Data From the ElaTION Trial
Ultrasound alone appears to be an effective diagnostic modality in thyroid nodules, confirming the recommendations of recent guidelines and the British Thyroid Association classification. However, findings also suggest caution regarding existing recommendations for conservative management of nondiagnostic (Thy1/Bethesda I) and atypical (Thy3a/Bethesda III) nodules. In those cases, ultrasound (U3-U5) features may help identify high-risk subgroups for more proactive management.
Authors
- Hisham Mehanna (ORCID: https://orcid.org/0000-0002-5544-6224)
- Jonathan J Deeks (ORCID: https://orcid.org/0000-0002-8850-1971)
- Rebecca Woolley (ORCID: https://orcid.org/0000-0001-5119-1431)
- Kristien Boelaert (ORCID: https://orcid.org/0000-0002-6435-177X)
- Gitta Madani (ORCID: https://orcid.org/0000-0001-8109-419X)
- Andrew Palmer (ORCID: https://orcid.org/0000-0003-3863-8491)
- Paul S. Sidhu (ORCID: https://orcid.org/0000-0003-1928-4077)
- Jasper Bekker
- Kanchana Rajaguru
- Paul Nankivell (ORCID: https://orcid.org/0000-0003-4664-6117)
- Catherine Moreman
- Tessa Fulton‐Lieuw (ORCID: https://orcid.org/0000-0002-9857-1834)
- Neil Sharma (ORCID: https://orcid.org/0000-0001-6776-0977)
- Judith Taylor (ORCID: https://orcid.org/0000-0001-8024-271X)
- Thaj Rehman
- Philip Da Forno
- Ram Vaidhyanath (ORCID: https://orcid.org/0009-0007-7475-7371)
Institutions
- Imperial College Healthcare NHS Trust (GB)
- King's College London (GB)
- Queen Elizabeth Hospital Birmingham (GB)
- Leicester Royal Infirmary (GB)
- Lister Hospital (GB)
- University Hospitals of Leicester NHS Trust (GB)
- Portsmouth Hospitals NHS Trust (GB)
- King's College Hospital NHS Foundation Trust (GB)
- King's College School (GB)
- St Mary's Hospital (GB)
- Basildon Hospital (GB)
- St. Mary’s Hospital (ZA)
- Cancer Research UK Clinical Trials Unit (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1210/clinem/dgae682
- Citations
- 5
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.79