The Convergence of Basal and Squamous: A Deep Dive into Basosquamous Cell Carcinoma – A Case Report

Basosquamous carcinoma is a rare, non-melanotic and aggressive variant of BCC having features of both basal cell component and squamous cell component diagnosed histopathologically.We report a case of Basosquamous carcinoma in a 75-year-old female patient who came with complaints of an ulcer over the left cheek for 1 month.Initially edge wedge biopsy was sent and it was to be BCC.Later on, the patient underwent a wide local excision biopsy.On microscopy sections showed skin and a tumour arising from the basal layer arranged in nests with peripheral palisading with foci of retraction artifacts and also desmoplastic stromal reaction.Also shows squamous differentiation with an increased mitotic rate.This case report highlights its distinctive histologic appearance and emphasises the aggressive nature of the tumour.